Thepatient is a 27 years old male with progressive wasting, fatigue and fever for
3 months. A tumor in the right leg was found 1 month ago. On admission, the
number of his CD4+ T cells was 13 cells/μl, CD8+ T cells 230 cells/μl, and the
CD4+ T cells/CD8+ T
cells was 0.01. His WBC was 4.26 × 109/L,
Hb was 94 g /L, and platelets were 317 × 109/L.
His HIV viral load was 150000 copies/ml. Other biochemical values are: ALT 23
U/L, AST 56 U/L, ALP 274 U/L, γ-GT 234 U/L, total bilirubin 8.7 umol/L, and
serum albumin 35.1 g/L. Upon confirmation of Kaposi’s sarcoma pathologically on
biopsy sample [1-4], the tumor mass on the leg was surgically removed at
Shanghai Public Health Clinical Center.
Theantiretroviral therapy continued and chemotherapy with liposome adriamycin 60
mg was administered after surgical tumor removal for 14 days. The number of
CD4+ T cells 7days after the first chemotherapy with liposome adriamycin was 5
cells/μl. The infection around the anus causes ulcers. Defecate more than 10 times
a day, it is light yellow and watery. Peripheral anal ulcer gradually increases
after local drug exchange treatment. Bone marrow infusion devices were used for
sigmoid colon fistula and intravenous catheterization of sigmoid colon. The perianal
biopsy was chronic inflammation with fungal infection.
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