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Tuesday 23 April 2019

Endobronchial Mucosa-Associated Lymphoid Tissue (MALT) Lymphoma with Atelectasis after Remission of Gastric MALT Lymphoma




Mucosa-associated Lymphoid Tissue (MALT) lymphoma comprised of monoclonal B cells is a type of non-Hodgkin’s lymphoma (NHL) that commonly occurs in the stomach. These lesions rarely metastasize from the stomach to other sites, especially to the airways. This report describes a patient with multiple bronchial MALT lymphoma lesions that developed after the remission of gastric MALT lymphoma. Furthermore, we discuss bronchoscopy was useful for both diagnosis and determining the extent of lesion expansion. A 90-year-old woman who had received radiation treatment for gastric MALT lymphoma seven years earlier was referred to our hospital after experiencing exertional dyspnea for three weeks. Physical examination demonstrated tachypnea; peripheral SpO2 was 82%; and breath sounds of the right lower lung field were absent. Laboratory examinations were within the normal range.

Chest CT showed severe and extensive area of stenosis, thickened bronchial walls, and polyp-like lesions from the trachea to the bilateral main bronchus, atelectasis of the right lower lobe, resulting in complete interruption of the right lower bronchus and right pleural fluid. Flexible bronchoscopy, performed with the consent of the patient, revealed edematous mucosa mimicking multiple nodules and a thickened bronchial wall irregularly extending from the carina to the bilateral main bronchus with mild stenosis. The right middle bronchus was completely obstructed.

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