Autologous fat grafting has become a popular treatment for volume
and contour defects in reconstructive and cosmetic surgeries. Illouz described
fat grafting to the breast using liposuctioned adipose tissue first and Bircoll
published this approach in 1987. Since then, autologous fat grafting has
gradually become popular as an option for cosmetic breast augmentation. Several modifications and refinements regarding fat harvesting,
processing, and injection have been made in many ways to increase graft
survival and enhance the predictability of this approach. No big impact on
outcome following fat grafting has been identified although these techniques
have been extensively studied and standardized.
Zuk et al. Isolated mesenchymal stem cells from adipose
tissue with the potential to differentiate into mesenchymal, including
adipogenic lineages In 2001. Adipose-Derived Stem Cells (ADSC) also displays
angiogenic properties through the release of mediators in a paracrine fashion.
ADSC have become attractive in regenerative medicine and are capable of being
used as a tool to enhance the survival of fat graft due to the ease of isolation
and abundant supply. The number of ADSC in adipose tissue is high In vivo.
Harvesting fat grafts by liposuction reduces the amount of ADSC.
No comments:
Post a Comment