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Friday 24 May 2019

Need to Design a Tool that can Assess Preoperative Factors which may Affect Cardiac Complications after Non-Cardiac Surgeries among CKD Patients





Each year, cardiac complications occur within 30 days after major non-cardiac surgery in more than 10 million people worldwide.Non Cardiac surgeries may improve the quality and patient’s life may get better or prolonged, however these surgeries may develop complications such as death from Cardiac causes, myocardial ischemia (MI), cardiac arrest or conjuctive heart failure. Unfortunately, a large proportion of ischemic episodes go undetected during surgery and in the postoperative period. Also, it is noticed that MI remains undiagnosed and physicians rarely administer therapy and plan secondary prevention in patients who have suffered from perioperative unstable angina or MI. The risk of subsequent cardiac events increases further due to lack of satisfactory management.

Knowing the clinical relevance of cardiac complications in the setting of non-cardiac surgery, preventive strategies for preoperative risk stratification have been proposed since 1977. Models were developed looking for associations between preoperative variables such as age, type of surgery, co-morbidities etc and the risk of cardiac complications in a cohort of patients undergoing non-cardiac surgeries called as “Derivation Cohort”. Variables that have independent predictive value using logistic regression analysis are incorporated into the risk index. The accuracy and validity of this risk index is then tested in a separate cohort called “validation cohort”.

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