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Thursday, 25 January 2018

Primary Squamous Papillary-Type Craniopharyngioma in the Cerebellopontine Angle: Report of Two Cases



Craniopharyngioma is a benign epithelial tumor that originates from the Rathke pouch and usually develops around the parasellarregion. By pathology the tumor is divided into two main types, the adamantinomatous type and squamous papillary type. In contrast to the usual parasellar location, primary craniopharyngioma developing in the Cerebellopontine (CP) angle is extremely rare, with only eleven cases reported to date. Ten of these cases were of the adamantinomatous type and one was of the squamous papillary type. Here, we report the neuroradiological findings from two additional cases of squamous papillary-type craniopharyngioma that developed in the CP angle and were isolated from the parasellar region.
The patient was therefore operated on via a lateral sub occipital approach. A cystic tumor was identified, with a rust-colored component being visible through the wall of the capsule. Following the opening of the cyst a motor oil-like fluid and semisolid component were drained. The 3rd nerve and pituitary stalk were identified beyond the arachnoid membrane with neither showing any sign of contact with the tumor (Figure 1e).
Postoperative MRI revealed near-total resection of the tumor (Figure 1f). Neuropathology showed that the wall of the cyst was composed of squamous epithelium with a papillary structure (Figure 1g). In contrast, the tumor contained keratinous material, cholesterin crystal and a fibrous inflammatory granuloma (Figure 1h), and was diagnosed as a squamous papillary-type craniopharyngioma. Postoperatively, the patient’s hearing acuity, facial numbness and gait disturbance improved. No sign of recurrence has been observed on follow-up examination for six years.


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