Pleomorphic Sarcoma
or Malignant Fibrous Histiocytoma is commonest soft tissue sarcoma but is rare
in Head and neck. Commonest site in Head and neck being Nasal cavity and para
nasal sinuses. It is more common in male. Tumor is diagnosed histologically
consisting of both histiocytes and fibroblast cells. Pleomorphic Sarcoma is
classified into primary and secondary types with mean age of presentation
between 6th and 7th decade. The treatment of choice for this tumor is surgery
with clear margins and adjuvant Radiotherapy. Prognosis remains poor even after
surgery with local and distant metastasis seen commonly.
Soft Tissue Sarcoma
encompasses (STS) a broad array of malignant tumors that are derived from cells
of mesenchymal origin at any anatomical site. The originating tissue is diverse
that includes bones, cartilage, muscular, fibrous, vascular, fatty and neural
tissue. Of all the soft tissue sarcomas only 5-20% occurs in the head and neck
region. The most common STS of the head and neck region are Rhabdomyosarcoma
followed by Malignant fibrous Histiocytoma, Fibrosarcoma and Neuro-fibrosarcoma.
The incidence of MFH seems to be the highest among various types of adult malignant
soft tissue sarcomas. Pleomorphic Sarcoma or Malignant Fibrous Histiocytoma
(MFH) is a rare primitive mesenchymal tumor showing both fibroblastic and
histiocytic differentiation. We report a case of Pleomorphic Sarcoma/ MFH and
the review of literature in relation to Pleomorphic Sarcoma.
No comments:
Post a Comment