Children Theophylline Toxicity: Case Report

Introduction:-
Theophylline, a bronchodilator, has been widely used for respiratory conditions like asthma and COPD. Despite its declining use due to safer alternatives, theophylline toxicity remains a concern, particularly in pediatric cases, as it can lead to severe complications such as seizures, metabolic disorders, and cardiovascular instability.

Case Report:-
A 5-year-old girl presented with theophylline toxicity after ingesting 2000 mg, leading to symptoms like abdominal pain, vomiting, and a generalized seizure. Despite initial outpatient management, her condition worsened, requiring intensive care. The child experienced tachycardia, hypotension, metabolic disturbances, and cerebral edema. Management included seizure control with midazolam, hemodynamic stabilization, and treatment for infectious complications. The patient recovered without lasting neurological deficits.

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Conclusion:-
This case highlights the critical importance of prompt and multidisciplinary management of theophylline toxicity. Preventive measures, such as keeping medications out of children’s reach, are essential. Early interventions, including activated charcoal and supportive care, can significantly improve outcomes in such cases.

Content Details:-

Corresponding author: Benani Mohame 

Full Length Article: Children Theophylline Toxicity: Case Report

Journal: Austin Journal of Clinical Case Reports

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