The Core Stabilization Guide Pyramid

                               http://austinpublishinggroup.com/yoga-physical-therapy/

Pyramids are visual conceptual models that are used by practitioners to illustrate where research is headed while serving as a metaphoric tool to present ideas to be practiced. The Core Stabilization Guide Pyramid represents an approach using a pyramid model for medical therapeutic yoga educators and practitioners to organize pranayama (breath) treatment modalities and lesson plans. Yoga educators have to alter the focus, content, and teaching goals for lessons and modalities. Use of this Pyramid does require changes in the way the concept of achieving core stability can be relevant for audiences or for the variety of patients exhibiting diverse pathology. In contrast to any other wellness guide, that represented a foundation or established process, the Core Stabilization Guide Pyramid depicts a patient’s total wellness picture. It is designed to address overstimulation as well as under stimulation using yoga techniques such as pranayama. The Core Stabilization Guide Pyramid is a graphic representation of the suggested Guidelines for those seeking to use Yoga as therapeutic medicine, and illustrates the main concept of the mind as having power over the body. For practitioners, one challenge is to find ways to effectively use the Core Stabilization Pyramid which involves teaching clients how to put the guidelines that are the specific words contained in the pyramid into action, each day, during each modality. Patients can meditate on one word while focusing on breath. Another challenge involves designing materials that adapt the messages of the Core Stabilization Guide Pyramid to a variety of audiences. One suggestion might be to construct a pyramid that can be hand held in order to visualize the protective effects from it. Alternatively, a large sized pyramid could be constructed and the patient can sit under it. Teaching materials and instructions should emphasize the key concepts of the Core Stabilization Guide Pyramid and should be clear, consistent, motivational, and culturally sensitive. Few educational materials are available to help practitioners with these challenges. In this clinical image, it is expected that practitioners will address the key changes that the Core Stabilization Guide Pyramid embodies and develop their own unique ideas and suggestions for using the Pyramid in a practice setting.

Utilization Pattern of Antenatal Care Services; an Example from South Egypt

                                        http://austinpublishinggroup.com/womens-health/

Antenatal Care (ANC) is a category of preventive healthcare aiming to provide regular check-ups that allow doctors or midwives to treat and prevent potential health problems along the pregnancy period while promoting healthy lifestyles that benefit both mother and child. The ANC is one of the four pillars of safe motherhood recommended strategies together with family planning, essential obstetric care “clean/safe delivery” and emergency obstetric care. Antenatal care from a skilled health professional is essential in order to monitor the pregnancy and reduce the risks for the mother and child during pregnancy and at delivery. To be most effective, it is recommended that all pregnant women should have at least four antenatal checkups during pregnancy, commencing as early as possible in the first trimester.

Interacting factors were found to shape ANC utilization pattern. Factors related to the socio demographic features of women include; ethnicity, residence, rural-urban, education, parity, age, marital status, occupation and family size. Structure on women’s decisions on ANC utilization, women’s position in the society, women’s knowledge, attitudes, beliefs, and culture were also found to correlate with ANC utilization Other determinants are related to health service characteristics” availability, accessibility, affordability”.

The ANC follow-up visits have become more prevalent in Egypt than ever before. The 2014 EDHS showed that the proportion of pregnant women who had at least four ANC visits reached about 83%. That proportion experienced a significant jump compared with that indicated in the 2008 EDHS, which reached 67%. Factors found to shape ANC utilization pattern included; mother age35 and older, child’s birth order, residence urban/ rural and the attained education.

An Introduction to Vector-Borne Diseases

                                       http://austinpublishinggroup.com/vector-borne-diseases/

Pathogens transmitted among animals, humans and plants by hematophagous arthropod vectors have been responsible for significant morbidity and mortality throughout human history. Together, Vector-Borne Diseases (VBDs) have accounted for more human disease and death during the last three centuries than all other causes combined. Currently, the World Health Organization (WHO) estimates that one-sixth of the illness and disability suffered worldwide can be attributed to VBDs, with more than half of the world’s population at risk. Every year, more than one billion people become infected and more than one million people die from VBDs, including African trypanosomiasis, American trypanosomiasis, dengue, leishmaniasis, malaria and schistosomiasis. In addition, many VBDs, such as lymphatic filariasis and onchocerciasis, are able to cause significant illness and suffering, contributing to a much larger overall burden of disease that can be traduced in Disability-Adjusted Life Years (DALYs).

VBDs are defined as infectious diseases of animals and humans caused by pathogenic agents such as bacteria, helminthes, protozoa and viruses transmitted by hematophagous arthropod vectors, which include bedbugs, biting midges, black flies, fleas, kissing bugs, lices, mites, mosquitoes, sand flies and ticks, among others. From the hematophagous arthropod vectors, mosquitoes are the leading vector for human infectious agents, meanwhile ticks are the leading vector for the vast majority of zoonosis worldwide. Furthermore, ticks are the vectors responsible of transmitting the greatest variety of infectious agents to animals and humans.

BVDs are most frequently found in tropical and subtropical climates of many developing countries and therefore several of them are listed at the WHO’s list of 18 Neglected Tropical Diseases (NTDs). NTDs can be characterized because they have subsisted in the poorest and most marginalized societies, where the lack of adequate sanitation, and close contact with infectious vectors and reservoirs prevail. However, several newly identified pathogens and vectors have triggered disease outbreaks all around the world, and previously controlled VBDs have re-emerged in new geographic areas.

Isolation and Molecular Characterization of a Porcine Rotavirus from Henan Province of China

                                              http://austinpublishinggroup.com/virology/

Porcine rotaviruses belong to the genus rotavirus in the family Reoviridae. Porcine rotaviruses have so far been divided into four serogroups, named as A, B, C, and E. Rotavirus appears as a wheel-like particle under negative staining electronic microscopy (EM). The rotavirus genome is composed of 11 double-stranded RNA segments, and the sizes range from 0.6 to 3.3 kb. VP4, VP6, and VP7 have recently become the focuses of research due to their unique biological functionalities. Based on the antigenicity of VP4 and VP7, group A rotavirus is divided into genotypes P and G. Group A porcine rotavirus is consist of 37P genotypes and 27 G genotypes.

The incubation period for acute porcine rotavirus infections in piglets usually ranges from 16 to 24h, the clinical symptoms for infections include depression, diarrhea, and a large amount of mucosal feces. Porcine rotaviruses mainly exist in the intestines of piglets at beginning of infection excrete into feces and spread throughout to other piglets by a fecal/oral route. Porcine rotavirus is very resistant to surrounding environment and disinfectants and viral infectivity in feces can last for 7-9 months at room temperature.

In last two years, pig herds with serious diarrhea have been reported in a large number of areas of China. During disease survey and diagnosis, a rotavirus, HN-001, was isolated from fecal samples of young piglet with acute diarrhea in Henan province of China. The virus isolation, molecular characterization, and its pathogenic evaluation in piglets will be described.

Physical and Metabolic Constraints on Feed Intake in Ruminants

                             http://austinpublishinggroup.com/veterinary-science-research/

The objective of this review article was to elucidate the main physical and metabolic constraints on feed intake in ruminants. Over the last 25 years, several major physical and metabolic regulators of feed intake in ruminants have been emphasized. Ruminal fill is one of the central regulators of Dry Matter Intake (DMI) under certain circumstances such as when feeds with low digestibility are fed. The dietary NDF, especially from forage, is a key contributor to reticulorumen fill. The greater NDF lowers the clearance rate of the rumen contents. Hence, the dietary NDF can be a key controller of feed intake in early and peak lactation cows that have not peaked in DMI or with limited rumen fiber pool. The NDF digestibility can significantly impact DMI. As NDF digestibility increases, the depressing effect of NDF on DMI weakens. Allen  stated that DMI rose by 0.17kg per unit rise in in vitro or in situ NDF digestibility. At higher NDF digestibility, the NDF will have a smaller impact on rumen distension. Thus, factors affecting NDF digestibility will affect DMI.

Among the important metabolic constraints of appetite are rumen concentrations of volatile fatty acids. Propionate injection into the portal vein has reduced feed intake in sheep. Propionate rather than acetate seems to cause hypophagia. Insulin secretion  and hepatic receptors have been proposed to mediate the hypophagic effects of propionate. In addition to the hepatic chemoreceptors, hepatic thermoreceptors may also control feed intake. Di Bella et al. heated the rat liver artificially and observed an increased chewing activity with reduced feed intake.

Feed intake is ultimately a psychological phenomenon integrating animal’s abilities to cope with changes in diet composition and metabolic demands. Thus, one must consider that the rumen or blood VFA is only one of many factors involved in feed intake. Illius and Jessop suggested that imbalances in nutrient supply both in the rumen, postrumen, and hepatic levels can reduce feed intake. They proposed that maximizing acetate use for lipogenesis needs a synchronous glucose supply. Glucose fuels lipogenesis by providing ATP and cofactors such as NADPH needed for fatty acid elongation. Thus, even the high production rate of acetate, if accompanied by adequate supply of other nutrients, May not necessarily down-regulate feed intake. The framework of Illius and Jessop  presumes that nutrient imbalances constrain feed intake via accumulation of excess metabolites such as acetate. Therefore, the animal targets a level of intake that minimizes nutrient imbalances. According to this framework, in the absence of adequate glucose, acetate will mount up and act as a hypophagic feedback.

Analyzing the Surgical Resection of Lung Cancer

                         http://austinpublishinggroup.com/vascular-medicine/index.php

The public health significance of lung cancer is reflected by the fact that this disease is one of the most common cancers in the world and it has a high case fatality rate. In the span of a few decades, lung cancer has gone from being a rare disease to the most common cancer worldwide and the greatest cause of cancer death globally. In 2008, lung cancer accounted for 13% (1.6 million) of the total cases and 18% (1.4 million) of the deaths, worldwide. Non-Small Cell Lung Cancer (NSCLC) comprises 80% of all cases. Mortality form lung cancer basically occurs through the metastatic spread of malignant cells to distant organs.

It is estimated that only 10% of new cases of bronchogenic carcinoma are potentially cured by surgery. Surgery is the treatment of choice for patients with stage I-II disease and selected patients with stage IIIA disease. Compared with radiotherapy in early stage disease, surgical treatment is the best alternative. In European countries the proportion of patients with diagnosed lung cancer who undergo surgery for lung cancer varies between 10 and 20% [5,6]. In the UK the resection rates in some areas are around 10%, but with quick access investigations the rate can easily be increased to 25%. In the United States it is estimated that approximately 25-30% of patients with NSCLC are offered surgery with curative intent.

Surgery for tuberculosis formed the basis for lung cancer surgery techniques, but after theintroduction of potent drugs for tuberculosis in the 1950’s, lung cancer surgery became themajor focus in chest surgery. The first successful pneumonectomy was performed in1933 by Drs. Graham and Singer in the USA. The rate of complications was high duringthe first years, with a reported early mortality of 30% in 1944. The rate of explorative thoracotomy without resection was also high (50%), by 1940 lobectomy andpneumonectomy were performed regularly for NSCLC with remarkable progress in early surgical results. During the next decades, radical pneumonectomy remained the golden standard, with a relatively low operative mortality, to be replaced in the 1960s by lobectomy as the standard in localized disease, resulting in a better surgical outcome and greater pulmonary reserve.

Immunization Outside the Expanded Program on Immunization in Abidjan City, Cote d’Ivoire

                                   http://austinpublishinggroup.com/vaccines-immunotherapeutics/

Immunization is one of the greatest achievements of public health policies. Second to access to drinking water, immunization is one of the most effective public health measure for controlling infectious diseases. It has significantly contributed to saving millions of children’s lives around the world particularly since the launch of the World Health Organization (WHO) Expanded Program on Immunization (EPI) in 1974 and its implementation. Public health accomplishments with immunization include eradication of smallpox in 1980 and the reduction in reported polio cases from 350,000 in 125 countries in 1988 to 9 in 2 countries in 2015. Other success from immunization includes the neonatal tetnus elimination Initiatives and its immunization and the immunization of pregnant women and women of childbearing age. Through the neonatal tetnus elimination and combined with clean and safe childbirths and umbilical cord care during the neonatal period, have helped to reduce neonatal tetanus cases in the world from 10538 to 2161 cases, 2603 to 835 cases in Africa, and in specifically in Côte d’Ivoire from 311 to 12 cases, from 1995 to 2014.

Vaccines and Immunization are among the most cost-effective health intervention. In the USA for example, smallpox eradication cost 100 million US dollars and that also enabled the world to yield about 1.35 billion annual savings over the 10 years following the eradication of the disease. There are even greater benefits in low-income countries where gaining a year of healthy life due to immunization was estimated at 14-20 US dollars, i.e. 7000-10 000 FCFA, assuming that a US dollar is worth 500 FCFA.

Implementation of the WHO EPI has been widespread across the world and its coverage reflected in the number of vaccines and target population in implementing countries including Côte d’Ivoire. However, in Côte d’Ivoire as in many other countries, coverage data on the non-EPI populations are scarce. For example a study among university of Abidjan-Cocody students showed only 3.7% coverage for Hepatitis B vaccination. This study however, did not give full coverage of non-EPI vaccination coverage in Abidjan. To compensate for the limited information, this study seeks to estimate non-EPI immunization coverage in Abidjan, Côte d’Ivoire. The study estimates immunization coverage for Tetanus, Hepatitis B, Meningitis, Yellow Fever and Typhoid Fever among people aged at least 2 years in Abidjan city. In addition we examine factors associated with the vaccination status and determine reasons for non-vaccination.

Use of Laser in the Treatment of Urethral Hemangioma

                                                     http://austinpublishinggroup.com/urology/

The urethral localization of anhemangiomas is very rare. Responsible for urethrorrhagia and/or hemospermia, the diagnosis is easily made by endoscopy. On the other hand, the treatment remains difficult because of the localization urethral. Nous report the case of a man of 28 years treated with Laser Nd YAG.A man of 28, with no particular history, had urethrorrhages associated with initial hematuria since the age of 20 years. A first endoscopic assessment, found a single hemangiomatous lesion located in the navicular fossa that was treated by electrocoagulation. Six months later, with a greater bleeding recurrence, a new urethrocystoscopy showed the appearance of a new hemangiomatous localization extended to the ventral side of the maxillary anterior urethra in the bulbar urethra and extending to on the meatus.

Arteriography was performed in search of a lesion that could be treated by embolization. This one did not find an arterial anomaly, but only a vascular puddle corresponding to the urethra at the venous time. Two years after, a new abundant urethrorrhagia, motivated an attempt of endoscopic treatment by electrocoagulation at the level of the most voluminous lesion located just under the striated sphincter. Due to the risk of secondary stenosis, coagulation was deliberately incomplete and bleeding recurrences were early.

The patient then presented daily urethrorrhages of low abundance without any repercussion or hemodynamic, nor anemia, but with a psychological and professional repercussion 3 months later, Laser Nd YAG coagulation was performed. The procedure was performed under general anesthesia, using an SLT Side Firing fiber equipped with the 40-watt lateral firing tip, positioned next to a cystoscope (Storz).

Management of Dengue Fever with Severe Thrombocytopenia in a Patient While on Warfarin: A Case Report

                                        http://austinpublishinggroup.com/tropical-medicine-care/

Dengue fever is a potentially lethal illness that is universally prevalent in the tropics. Dengue hemorrhagic fever is characterized by a ‘leakage phase’ (or critical phase) usually lasting 48 hours following an initial febrile phase. During the leakage phase, an increase in capillary permeability leads to extravasation of fluid and haemoconcentration. During the latter part of febrile phase and early leakage phase (or even later), there is a steady drop in platelet count. Some patients with dengue fever will develop severe thrombocytopenia during the course of the illness even without going into a critical phase and the platelet count does not necessarily indicate the severity of infection. At occasions, it can drop as low as 500/μl in previously healthy individuals (normal platelet count in a healthy adult: 150,000-400,000/μl). The exact mechanism of this drop is unclear but presumed to be immunological. The low platelet count leaves the patient at a significant risk of spontaneous bleeding. The management is further complicated by pre-existing co-morbidities that interfere with the usual therapeutic guidelines. Use of oral anticoagulants is one such situation where management of dengue fever could be challenging. We report a patient with severe dengue infection with very low platelet counts without bleeding manifestations who was on anticoagulation with warfarin for atrial fibrillation with severe mitral regurgitation awaiting prosthetic mitral valve replacement.

A fifty one year old Sri Lankan male, presented with fever for three days and arthralgia, myalgia and retro orbital headache. There were no other systemic symptoms to suggest any focus of infection. He had mitral regurgitation following papillary muscle rupture due to a myocardial infarction one year ago complicated with atrial fibrillation for which he was on anticoagulant therapy with warfarin. His target PT INR (Prothrombin Time International Normalized Ratio) of 2-3, maintained with 7mg of warfarin per day. His other medications included; digoxin, and a combination of hydrochlorothiazide and furosemide. His 2D echocardiography done on August-2016 revealed grade 1V mitral regurgitation with left ventricular ejection fraction of 60%. On admission, he was hemodynamically stable with an irregularly irregular pulse at a rate of 76 beats per minute and a blood pressure of 110/60mmHg. All the peripheral pulses were felt and capillary refilling time was <2 seconds. On auscultation, there was a pan-systolic murmur at cardiac apex with radiation to axilla.

Fifty (50) Year Experience at the NBRL, Boston, Massachusetts to Study the Survival and Function of Fresh, Liquid, and Freeze Preserved Human and Baboon Red Blood Cells, Platelets, and Plasma Clotting Proteins

                                  http://austinpublishinggroup.com/thrombosis-haemostasis/

Between 1965 and 1974, the NBRL was located at the Chelsea Naval Hospital which was renamed the Boston Naval Hospital. Two books were written to report the studies performed and the data reported during this period: Blood Banking and the Use of Frozen Blood Products and Hypovolemic Anemia of Trauma: The Missing Blood Syndrome. In addition a monograph published in 2006 reported the 30-year experience at the NBRL to study the survival and function of fresh, liquid preserved, and frozen baboon RBC, platelets, and plasma clotting proteins: The survival and function of baboon red blood cells, platelets and plasma proteins: a review of the experience from 1972 to 2002 at the Naval Blood Research Laboratory, Boston, Massachusetts. In the 65 peer-reviewed NBRL publications reported in the monograph, the bleeding time measurement was shown to be an accurate method to assess the hemostatic function of fresh, liquid preserved and cryopreserved baboon red blood cells, platelets, and plasma clotting proteins.

In 2007, the monograph: Non-surgical bleeding diathesis in anemic thrombocytopenic patients: Role of temperature, RBC, platelets, and plasma clotting proteins was published. This monograph reports that nonsurgical blood loss correlated to the bleeding time in normal volunteers and in patients. The bleeding time measurement was affected by the temperature and the function of the RBC, platelets, and plasma clotting proteins. The monograph summarized 45 peer-reviewed NBRL publications which measured the bleeding time in normal volunteers and patients to assess the hemostatic effect of the red blood cells, platelets, and plasma proteins to reduce the bleeding time and reduce the nonsurgical blood loss. The monograph identified that the temperature had a significant effect on the bleeding time. Hypothermia produced a significant increase in the bleeding time and increase in nonsurgical blood loss and increase in temperature reduced the bleeding time and reduced the nonsurgical blood loss.

Sustainable Approach to Modify the CPD Process for Knit Garments and Analysis the Effect of Curing Treatment on CPD

                                  http://austinpublishinggroup.com/textile-engineering/

The purpose of thestudy is to minimize the energy load of Cold pigment dyeing (CPD) process by minimizing the process steps. As a representative effort in this direction, the current paper describes the effect of curing treatment on Cold pigment dyed garments considering different properties .Samples pretreatment were done in the same bath and same method followed for both samples. In case of dyeing, two different methods i.e. existing (Pad-dry-cure) and experimental (pad-dry) were used to develop the samples. Prepared samples were evaluated in terms of CMC_ΔE value, color fastness properties, drape co-efficient, GSM, fabric strength and surface morphology respectively. Results of the study evinced that experimental process is better than existing process by considering process time and energy savings. Color fastness value of the experimental sample offer comparatively better values than the existing process while other results are within range. Experimental process can reduced up to 6% processing time along with 2.35 Kw power savings for each batch. The experimental (pad-dry) process of CPD will provide a strong economical benchmark for the garments dyeing industry to adopt this sustainable process.

In the fast fashion world when time to market is paramount, the concept of garment dyeing post make up is increasingly adopted by manufacturers. Garment dyeing can be defined as the “application of color to fully fashioned apparel articles, may be in the form of garments cut and sewn either prepared or unprepared knitted fabrics and then dyed, garments and / or components knitted from either prepared or unprepared yarn and then dyed, The benefits of processing good through garment dyeing procedure revolve around quick response with minimize lead time and improved inventory control.

It is also increased the challenges of achieving the unique ,fashionable & value added products, while remaining comparative in price similar to reduction in operating margins, the dyeing process should be more economical while producing high value product. Pigments are kinds of insoluble colorants used for fibers, yarns and garments very commonly, which can retain stable chemical structure throughout the coloration process in its dispersed solution. Water-based pigment systems, are eco-friendly pathways. Pigments are dispersed into water with the assist of auxiliaries, such as dispersants, emulsifiers, anti-setting agents, etc. Water-based pigment has been widely applied in coloration for textiles, paints, architecture, and wood and so on. The Cold pigment dyeing is one kind of garments dyeing process which give an uneven look at low temperature. This process is also referred to as wave dyeing, top dyeing, oil wash and random dyeing. It is a simple and eco-friendly pigment dyeing process obtained by the usage of a binder, fixer along with pigments (any color).

HLA Incompatible Successful Renal Transplantation Across Bw4/Bw6 Alleles in Two Patients

                                      http://austinpublishinggroup.com/transplantation-sciences/

AMR: Antibody Mediated Rejection; BSHI: British Society for Histocompatibility and Immunogenetics; CDCXM: CDC Cross-Match; CREG: Cross Reactive Group; DSA: Donor Specific Antibody; FCXM: Flowcytometry Cross-Match; HLA: Human Leukocyte antigen; HLAi: HLA incompatible; IVIg: Intra Venous Immuno globulin; KSS: UK Living Donor Kidney Sharing Scheme; MFI: Mean Fluorescence Intensity; MMF: Mycophenolate Mofetil μ mol/L: Micromoles/litre; PRA: Panel Reactive Antibody; POD: Post Operative Day; SAB: Single Antigen Bead.

HLA Incompatible (HLAI) renal transplantation with desensitization is being increasingly performed in Northern Ireland because it results in better quality of life and improved survival compared to long term maintenance dialysis. Risk stratification for potential recipients in the United Kingdom is performed according to British Society of Histocompatibility and Immunogenetics (BSHI) / British Transplant Society (BTS) guidelines, which involves comprehensive evaluation by a combination of Complement Dependent Cytotoxicity Cross-Match (CDCXM), Flowcytometry Cross-Match (FCXM) and Luminex Single Antigen Bead (SAB) assay, and correlation with sensitization history. Transplanting successfully across a broad specificity such as HLA- Bw4 or Bw6 may prove more difficult, because non–DSA reacting with Bw4 or Bw6 epitopes could have an additive effect and hence greater overall reactivity even if reactivity against the donor mismatched allele is low. In this paper the workup leading to successful outcome of two HLAI transplants performed in Belfast City Hospital is presented. Maintenance immunosuppression was with the triple drug regimen of Prednisolone, Mycophenolate Mofetil (MMF) and Tacrolimus.

Skin-On-Chips for Drug Discovery of Chronic Wounds

                                       http://austinpublishinggroup.com/tissue-engineering/

Diabetic foot ulcers, venous leg ulcers, and pressure ulcers contribute to majority of chronic wounds. The importance of improved wound healing measure is especially well demonstrated by the healing problems in diabetes. It is estimated that about 30% of all the costs for diabetes relates to wound care in USA. In addition, 2.4-4.5 million people have been reported to have chronic lower extremity ulcers in USA only. Pressure ulcers and leg ulcers, including venous ulcers, cost as high as $8 billion annually in USA, and are a significant cause of morbidity in aged population. Although a slow wound repair is a self-limiting process and not a pathogenesis in itself, severe chronic wounds can also lead to chronic inflammatory diseases, fibrosis, and cancer, comprising stifling economic health care burdens.

Wound healing in clinical settings relies primarily on enabling the natural course of epidermal tissue regeneration. In many cases, the involved processes and the progress of regeneration may be insufficient to save severely injured patients. Especially difficult are various types of chronic wounds, with diabetic wounds being the most severe type. Current conventional treatment of chronic wound comprises mainly approaches with various types of dressings, bandages, and antibiotics. Several skin substitutes have reached the market place for second-line therapy of chronic ulcers, but they have not had the impact that was predicted. In severe cases where the wounds do not heal, amputation is the only treatment option that is available. Therefore, there is a great need for better wound healing treatments, in particular to cure diabetic and other chronic wounds. Another challenge in clinics is the lack of available evidence demonstrating efficacy for the advanced wound care products. Personalized medicine based on a systematic evaluation of patients and their wound conditions comprise an attractive approach to accelerate and strengthen wound healing processes in the future.