http://austinpublishinggroup.com/austin-dental-sciences/
Therapeuticoptions for the treatment of candidiasis are mainly azole, polyene and
echinocandin type antibiotics. Unfortunately, the clinical use of these agents
has been limited due to their toxicity and resistance factors, contributing to
high rates of morbidity and mortality. In recent decades, research on medicinal
plants has been an alternative in the discovery of new biocomponents for
various applications in folk medicine. The use of essential oils extracted from
different types of plants, showed several indications, as antiseptic, antifungal
and antibacterial actions.
Thegenus Elionurus presents approximately 45 species. It occurs in Africa,
Asia, North America and South America. Elionurus muticus is a grass of
the Brazilian pampas known as Brazilian lemongrass. This has aroused
considerable interest in the phytochemical industry. It presents antioxidant
activity related to the content of its phenolic compounds. It is notable for
containing antiseptic, sudoriferous and febrile properties. Produces essential
oil in all its extension: in the aerial
part, leaves and inflorescences, as in the roots. However, both the composition
and the yield are variable according to the region of cultivation and the
seasonality.
Despite this, this essential oil may be rich in citral, which is
a mixture of two geometric isomers known as geranians and nerals. Some
pharmacological properties of citral have been reported in the literature,
including antitumor, bronchodilator, antiprotozoal and antimicrobial effects. Based
on the literature data, the objective of this work was to evaluate the in
vitro antimicrobial activity of Elionurus muticus essential oil on
the Candida spp. Strains by determining the Minimum Inhibitory
Concentration (MIC) and Minimum Fungicidal Concentration (CFM).
No comments:
Post a Comment